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GENERAL
TITLE
CRYSTAL STRUCTURE OF DDB1-CRBN-BRD4(BD1) COMPLEX BOUND TO DBET6 PROTAC.
DATE LAST MODIFIED
4 Dec 2019
RELEASE
30 May 2018
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65 2 2
RESOLUTION RANGE HIGH
3.33
RESOLUTION RANGE LOW
49.793
PUBMED ID
DOI
10.1038/S41589-018-0055-Y
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q16531 DDB1, XAP1 TRICHOPLUSIA NI HUMAN
DDB P127 SUBUNIT,DNA DAMAGE-BINDING PROTEIN A,DDBA ...
Mutations
Q96SW2 CRBN, AD-006 TRICHOPLUSIA NI HUMAN -- Mutations
O60885 BRD4, HUNK1 ESCHERICHIA COLI HUMAN
PROTEIN HUNK1
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402