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GENERAL
TITLE
CRYSTAL STRUCTURE OF PDE5 IN COMPLEX WITH INHIBITOR LW1805
DATE LAST MODIFIED
10 Oct 2018
RELEASE
19 Sept 2018
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
24
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01209
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O76074 PDE5A, PDE5 ESCHERICHIA COLI BL21 HUMAN
CGMP-BINDING CGMP-SPECIFIC PHOSPHODIESTERASE,CGB-P ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402