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GENERAL
TITLE
CRYSTAL STRUCTURE OF BRUTON'S TYROSINE KINASE IN COMPLEX WITH INHIBITOR 2E
DATE LAST MODIFIED
28 Nov 2018
RELEASE
26 Sept 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.8B01147
PDBe
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LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q06187 BTK, AGMX1, ATK, BPK UNIDENTIFIED BACULOVIRUS HUMAN
AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...
Mutations
Q06187 BTK, AGMX1, ATK, BPK UNIDENTIFIED BACULOVIRUS HUMAN
AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...
Mutations
Q06187 BTK, AGMX1, ATK, BPK UNIDENTIFIED BACULOVIRUS HUMAN
AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...
Mutations
Q06187 BTK, AGMX1, ATK, BPK UNIDENTIFIED BACULOVIRUS HUMAN
AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...
Mutations
Q06187 BTK, AGMX1, ATK, BPK UNIDENTIFIED BACULOVIRUS HUMAN
AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...
Mutations
Q06187 BTK, AGMX1, ATK, BPK UNIDENTIFIED BACULOVIRUS HUMAN
AGAMMAGLOBULINEMIA TYROSINE KINASE,ATK,B-CELL PROG ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402