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GENERAL
TITLE
CRYSTAL STRUCTURE OF TRK-A COMPLEXED WITH A SELECTIVE INHIBITOR CH7057288
DATE LAST MODIFIED
19 Dec 2018
RELEASE
6 Dec 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
H 3 2
RESOLUTION RANGE HIGH
2.76
RESOLUTION RANGE LOW
82.54
PUBMED ID
DOI
10.1158/1535-7163.MCT-17-1180

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P04629 NTRK1, MTC, TRK, TRKA SPODOPTERA FRUGIPERDA HUMAN
NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1,TRK1- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402