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GENERAL
TITLE
STRUCTURE OF CYTOCHROME P450 2D6 (CYP2D6) BACE1 INHIBITOR COMPLEX
DATE LAST MODIFIED
25 Dec 2019
RELEASE
11 Jan 2017
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.75
RESOLUTION RANGE LOW
39.07
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.6B01451
PDBe
5TFU
Chains
| Structure Chain | Target Protein | Gene | Expression System | Organism | Synonims | Actions |
|---|---|---|---|---|---|---|
| P10635 | CYP2D6, CYP2DL1 | ESCHERICHIA COLI DH5[ALPHA] | HUMAN | CYPIID6,CHOLESTEROL 25-HYDROXYLASE,CYTOCHROME P450 ... | Mutations | |
| P10635 | CYP2D6, CYP2DL1 | ESCHERICHIA COLI DH5[ALPHA] | HUMAN | CYPIID6,CHOLESTEROL 25-HYDROXYLASE,CYTOCHROME P450 ... | Mutations | |
| P10635 | CYP2D6, CYP2DL1 | ESCHERICHIA COLI DH5[ALPHA] | HUMAN | CYPIID6,CHOLESTEROL 25-HYDROXYLASE,CYTOCHROME P450 ... | Mutations | |
| P10635 | CYP2D6, CYP2DL1 | ESCHERICHIA COLI DH5[ALPHA] | HUMAN | CYPIID6,CHOLESTEROL 25-HYDROXYLASE,CYTOCHROME P450 ... | Mutations |
NGL Viewer is used for the molecular visualization.
- AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
- AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402