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GENERAL
TITLE
TGF-BETA RECEPTOR TYPE 1 KINASE DOMAIN (T204D) IN COMPLEX WITH 6-[4- (3-CHLORO-4-FLUOROPHENYL)-1-(2-HYDROXYETHYL)-1H-IMIDAZOL-5- YL]IMIDAZO[1,2-B]PYRIDAZINE-3-CARBONITRILE
DATE LAST MODIFIED
17 Nov 2021
RELEASE
5 Feb 2020
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.67
RESOLUTION RANGE LOW
78.11
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.9B00552
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P36897 TGFBR1, ALK5, SKR4 SPODOPTERA FRUGIPERDA HUMAN
TGFR-1,ACTIVIN A RECEPTOR TYPE II-LIKE PROTEIN KIN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402