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GENERAL
TITLE
DIMETHYL FUMARATE IS AN ALLOSTERIC COVALENT INHIBITOR OF THE P90 RIBOSOMAL S6 KINASES
DATE LAST MODIFIED
31 Oct 2018
RELEASE
30 May 2018
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
47
PUBMED ID
DOI
10.1038/S41467-018-06787-W

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P18654 RPS6KA3, MAPKAPK1B, RPS6KA-RS1, RSK2 ESCHERICHIA COLI MOUSE
S6K-ALPHA-3,90 KDA RIBOSOMAL PROTEIN S6 KINASE 3,P ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402