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GENERAL
TITLE
APPLICATION OF OFF-RATE SCREENING IN THE IDENTIFICATION OF NOVEL PAN- ISOFORM INHIBITORS OF PYRUVATE DEHYDROGENASE KINASE
DATE LAST MODIFIED
5 Apr 2017
RELEASE
22 Feb 2017
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 64
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
29.37
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.6B01478
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q15119 PDK2, PDHK2 ESCHERICHIA COLI BL21(DE3) HUMAN
PYRUVATE DEHYDROGENASE KINASE ISOFORM 2,PDKII
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402