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GENERAL
TITLE
HUMAN 20S PROTEASOME COMPLEX WITH BORTEZOMIB AT 2.1 ANGSTROM
DATE LAST MODIFIED
21 Nov 2018
RELEASE
17 Aug 2016
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.1
RESOLUTION RANGE LOW
170.45
PUBMED ID
DOI
10.1126/SCIENCE.AAF8993
PDBe
--
LIGANDS
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P25787 -- -- HUMAN
MACROPAIN SUBUNIT C3,MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
P25789 -- -- HUMAN
MACROPAIN SUBUNIT C9,MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
O14818 -- -- HUMAN
PROTEASOME SUBUNIT RC6-1,PROTEASOME SUBUNIT XAPC7
Mutations
P28066 -- -- HUMAN
MACROPAIN ZETA CHAIN,MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
P25786 -- -- HUMAN
30 KDA PROSOMAL PROTEIN,PROS-30,MACROPAIN SUBUNIT ...
Mutations
P25788 -- -- HUMAN
MACROPAIN SUBUNIT C8,MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
P60900 -- -- HUMAN
27 KDA PROSOMAL PROTEIN,P27K,MACROPAIN IOTA CHAIN, ...
Mutations
Q99436 -- -- HUMAN
MACROPAIN CHAIN Z,MULTICATALYTIC ENDOPEPTIDASE COM ...
Mutations
P49720 -- -- HUMAN
PROTEASOME CHAIN 13,PROTEASOME COMPONENT C10-II,PR ...
Mutations
P49721 -- -- HUMAN
MACROPAIN SUBUNIT C7-I,MULTICATALYTIC ENDOPEPTIDAS ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402