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3D Structure View

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GENERAL
TITLE
LSD1-COREST1 IN COMPLEX WITH QUINAZOLINE-DERIVATIVE REVERSIBLE INHIBITOR
DATE LAST MODIFIED
28 Feb 2018
RELEASE
21 Sept 2016
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/REPRESSOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
3.3
RESOLUTION RANGE LOW
99.85
PUBMED ID
DOI
10.1126/SCIADV.1601017

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O60341 KDM1A, AOF2, KDM1, KIAA0601, LSD1 ESCHERICHIA COLI BL21 HUMAN
BRAF35-HDAC COMPLEX PROTEIN BHC110,FLAVIN-CONTAINI ...
Mutations
Q9UKL0 RCOR1, KIAA0071, RCOR ESCHERICHIA COLI BL21(DE3) HUMAN
PROTEIN COREST
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402