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3D Structure View

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GENERAL
TITLE
THE X-RAY CO-CRYSTAL STRUCTURE OF HUMAN CDK6 AND ABEMACICLIB.
DATE LAST MODIFIED
19 Oct 2016
RELEASE
24 Aug 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 4
RESOLUTION RANGE HIGH
2.27
RESOLUTION RANGE LOW
72
PUBMED ID
DOI
10.1158/1535-7163.MCT-16-0300
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q00534 CDK6, CDKN6 SPODOPTERA FRUGIPERDA HUMAN
CELL DIVISION PROTEIN KINASE 6,SERINE/THREONINE-PR ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402