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GENERAL
TITLE
POTENT, REVERSIBLE METAP2 INHIBITORS VIA FRAGMENT BASED DRUG DISCOVERY
DATE LAST MODIFIED
15 Jun 2016
RELEASE
25 May 2016
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
1.6
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.BMCL.2016.04.072

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P50579 METAP2, MNPEP, P67EIF2 SPODOPTERA FRUGIPERDA HUMAN
METAP 2,INITIATION FACTOR 2-ASSOCIATED 67 KDA GLYC ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402