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GENERAL
TITLE
STRUCTURE OF MDM2 WITH LOW MOLECULAR WEIGHT INHIBITOR WITH ALIPHATIC LINKER.
DATE LAST MODIFIED
31 Jan 2018
RELEASE
17 May 2017
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 2 21 21
RESOLUTION RANGE HIGH
1.85
RESOLUTION RANGE LOW
85.7
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.7B00104
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q00987 MDM2 ESCHERICHIA COLI HUMAN
DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...
Mutations
Q00987 MDM2 ESCHERICHIA COLI HUMAN
DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...
Mutations
Q00987 MDM2 ESCHERICHIA COLI HUMAN
DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...
Mutations
Q00987 MDM2 ESCHERICHIA COLI HUMAN
DOUBLE MINUTE 2 PROTEIN,HDM2,ONCOPROTEIN MDM2,P53- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402