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GENERAL
TITLE
LACTATE DEHYDROGENASE IN COMPLEX WITH HYDROXYLACTAM INHIBITOR COMPOUND 9: (6R)-3-[(2-CHLOROPHENYL)SULFANYL]-4-HYDROXY-6-(3-HYDROXYPHENYL)-6- (THIOPHEN-3-YL)-5,6-DIHYDROPYRIDIN-2(1H)-ONE
DATE LAST MODIFIED
9 Nov 2016
RELEASE
14 Sept 2016
OBSOLETE
CLASSIFICATION
OXIREDUCTASE/OXIREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.05
RESOLUTION RANGE LOW
37.8
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.6B00190

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A,CELL PROLIFERATION-INDUCING GENE 19 PROTEIN, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402