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GENERAL
TITLE
LINKED KDM5A JMJ DOMAIN BOUND TO THE INHIBITOR N11 [3-({1-[2-(4,4- DIFLUOROPIPERIDIN-1-YL)ETHYL]-5-FLUORO-1H-INDAZOL-3-YL}AMINO) PYRIDINE-4-CARBOXYLIC ACID]
DATE LAST MODIFIED
3 Aug 2016
RELEASE
27 Jul 2016
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.569
RESOLUTION RANGE LOW
32.98
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2016.06.006

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P29375 KDM5A, JARID1A, RBBP2, RBP2 ESCHERICHIA COLI HUMAN
HISTONE DEMETHYLASE JARID1A,JUMONJI/ARID DOMAIN-CO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402