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GENERAL
TITLE
STRUCTURE OF THE PRIMARY ONCOGENIC MUTANT Y641N HS/ACPRC2 IN COMPLEX WITH A PYRIDONE INHIBITOR
DATE LAST MODIFIED
22 Nov 2017
RELEASE
4 May 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.98
RESOLUTION RANGE LOW
115.13
PUBMED ID
DOI
10.1038/NCOMMS11384
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q15910 EZH2, EZH2, KMT6 SPODOPTERA FRUGIPERDA GREEN ANOLE, HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
Q15910 EZH2, EZH2, KMT6 SPODOPTERA FRUGIPERDA GREEN ANOLE, HUMAN
ENX-1,ENHANCER OF ZESTE HOMOLOG 2,LYSINE N-METHYLT ...
O75530 EED SPODOPTERA FRUGIPERDA HUMAN
HEED,WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLAS ...
Mutations
O75530 EED SPODOPTERA FRUGIPERDA HUMAN
HEED,WD PROTEIN ASSOCIATING WITH INTEGRIN CYTOPLAS ...
Mutations
Q15022 SUZ12, CHET9, JJAZ1, KIAA0160 SPODOPTERA FRUGIPERDA HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
Mutations
Q15022 SUZ12, CHET9, JJAZ1, KIAA0160 SPODOPTERA FRUGIPERDA HUMAN
CHROMATIN PRECIPITATED E2F TARGET 9 PROTEIN,CHET 9 ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402