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3D Structure View

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GENERAL
TITLE
CDK8-CYCC IN COMPLEX WITH 8-[3-CHLORO-5-(1-METHYL-2,2-DIOXO-2, 3- DIHYDRO-1H-2L6-BENZO[C]ISOTHIAZOL-5-YL)-PYRIDIN- 4-YL]-1-OXA-3,8- DIAZA-SPIRO[4.5]DECAN-2-ONE
DATE LAST MODIFIED
24 Feb 2016
RELEASE
3 Feb 2016
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.38
RESOLUTION RANGE LOW
86.58
PUBMED ID
DOI
10.1021/ACS.JMEDCHEM.5B01685
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P49336 CDK8 SPODOPTERA FRUGIPERDA HUMAN
CELL DIVISION PROTEIN KINASE 8,MEDIATOR COMPLEX SU ...
Mutations
P24863 CCNC SPODOPTERA FRUGIPERDA HUMAN
SRB11 HOMOLOG,HSRB11
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402