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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN CORTICOTROPIN-RELEASING FACTOR RECEPTOR 1 (CRF1R) IN COMPLEX WITH THE ANTAGONIST CP-376395 IN A HEXAGONAL SETTING WITH TRANSLATIONAL NON-CRYSTALLOGRAPHIC SYMMETRY
DATE LAST MODIFIED
6 Dec 2017
RELEASE
29 Jun 2016
OBSOLETE
CLASSIFICATION
SIGNALING PROTEIN
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 6
RESOLUTION RANGE HIGH
3.18
RESOLUTION RANGE LOW
45.48
PUBMED ID
DOI
10.2174/1874467210666170110114727

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P34998 CRHR1, CRFR, CRFR1, CRHR, E, RB51ORF131 TRICHOPLUSIA NI HUMAN
CRFR-1,CORTICOTROPIN-RELEASING HORMONE RECEPTOR 1C ...
Mutations
P34998 CRHR1, CRFR, CRFR1, CRHR, E, RB51ORF131 TRICHOPLUSIA NI HUMAN
CRFR-1,CORTICOTROPIN-RELEASING HORMONE RECEPTOR 1C ...
Mutations
P34998 CRHR1, CRFR, CRFR1, CRHR, E, RB51ORF131 TRICHOPLUSIA NI HUMAN
CRFR-1,CORTICOTROPIN-RELEASING HORMONE RECEPTOR 1C ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402