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GENERAL
TITLE
CRYSTAL STRUCTURE OF COT KINASE DOMAIN IN COMPLEX WITH 5-(5-(1H-INDOL- 3-YL)-1H-PYRROLO[2,3-B]PYRIDIN-3-YL)-1,3,4-OXADIAZOL-2-AMINE
DATE LAST MODIFIED
29 May 2019
RELEASE
6 May 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.33
RESOLUTION RANGE LOW
73.77
PUBMED ID
DOI
10.1074/JBC.M115.648097
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P41279 MAP3K8, COT, ESTF SPODOPTERA FRUGIPERDA HUMAN
CANCER OSAKA THYROID ONCOGENE,PROTO-ONCOGENE C-COT ...
Mutations
P41279 MAP3K8, COT, ESTF SPODOPTERA FRUGIPERDA HUMAN
CANCER OSAKA THYROID ONCOGENE,PROTO-ONCOGENE C-COT ...
Mutations
P41279 MAP3K8, COT, ESTF SPODOPTERA FRUGIPERDA HUMAN
CANCER OSAKA THYROID ONCOGENE,PROTO-ONCOGENE C-COT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402