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GENERAL
TITLE
CRYSTAL STRUCTURE OF C-MET IN COMPLEX WITH (S)-5-(8-FLUORO-3-(1-(3-(2- METHOXYETHOXY)QUINOLIN-6-YL)ETHYL)-[1,2,4]TRIAZOLO[4,3-A]PYRIDIN-6- YL)-3-METHYLISOXAZOLE
DATE LAST MODIFIED
25 Mar 2015
RELEASE
11 Mar 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.85
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM501913A
PDBe
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LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P08581 MET TRICHOPLUSIA NI HUMAN
HGF RECEPTOR,HGF/SF RECEPTOR,PROTO-ONCOGENE C-MET, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402