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GENERAL
TITLE
CRYSTAL STRUCTURE OF THE FLT3 KINASE DOMAIN BOUND TO THE INHIBITOR QUIZARTINIB (AC220)
DATE LAST MODIFIED
20 Nov 2019
RELEASE
15 Apr 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
3.2
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1371/JOURNAL.PONE.0121177
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P36888 FLT3, CD135, FLK2, STK1 UNIDENTIFIED BACULOVIRUS HUMAN
FL CYTOKINE RECEPTOR,FETAL LIVER KINASE-2,FLK-2,FM ...
Mutations
P36888 FLT3, CD135, FLK2, STK1 UNIDENTIFIED BACULOVIRUS HUMAN
FL CYTOKINE RECEPTOR,FETAL LIVER KINASE-2,FLK-2,FM ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402