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GENERAL
TITLE
DISCOVERY OF NOVEL OXAZEPINE AND DIAZEPINE CARBOXAMIDES AS TWO NEW CLASSES OF HEAT SHOCK PROTEIN 90 INHIBITORS
DATE LAST MODIFIED
1 Jun 2016
RELEASE
4 Mar 2015
OBSOLETE
CLASSIFICATION
CHAPERONE/CHAPERONE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
1.84
RESOLUTION RANGE LOW
55.404
PUBMED ID
DOI
10.1016/J.BMCL.2015.01.023
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P07900 HSP90AA1, HSP90A, HSPC1, HSPCA SPODOPTERA FRUGIPERDA HUMAN
HEAT SHOCK 86 KDA,HSP86,LIPOPOLYSACCHARIDE-ASSOCIA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402