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4X6P

3D Structure View

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GENERAL
TITLE
FACTOR XIA (PICHIA PASTORIS; C500S [C122S]) IN COMPLEX WITH THE INHIBITOR (2E)-N-{(1S)-1-[4-(3-AMINO-1H-INDAZOL-6-YL)-1H-IMIDAZOL-2- YL]-2-PHENYLETHYL}-3-[5-CHLORO-2-(1H-TETRAZOL-1-YL)PHENYL]PROP-2- ENAMIDE
DATE LAST MODIFIED
29 Jul 2020
RELEASE
18 Feb 2015
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
1.93
RESOLUTION RANGE LOW
41.27
PUBMED ID
DOI
10.1016/J.BMCL.2015.01.028

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03951 F11 KOMAGATAELLA PASTORIS HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
P03951 F11 KOMAGATAELLA PASTORIS HUMAN
FXI,PLASMA THROMBOPLASTIN ANTECEDENT,PTA
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402