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4WVL

3D Structure View

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GENERAL
TITLE
STRUCTURE-GUIDED DOT1L PROBE OPTIMIZATION BY LABEL-FREE LIGAND DISPLACEMENT
DATE LAST MODIFIED
26 Aug 2015
RELEASE
3 Dec 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
2.4
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/CB500796D

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q8TEK3 DOT1L, KIAA1814, KMT4 ESCHERICHIA COLI HUMAN
DOT1-LIKE PROTEIN,HISTONE H3-K79 METHYLTRANSFERASE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402