4WOV logo

4WOV

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED WITH BMS-066 AKA 2-METHOXY-N-({6-[3-METHYL-7-(METHYLAMINO)- 3,5,8,10-TETRAAZATRICYCLO[7.3.0.0, 6]DODECA-1(9),2(6),4,7,11-PENTAEN- 11-YL]PYRIDIN-2-YL}METHY L)ACETAMIDE
DATE LAST MODIFIED
22 Nov 2017
RELEASE
18 Mar 2015
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1
RESOLUTION RANGE HIGH
1.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1074/JBC.M114.619502

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P29597 TYK2 UNIDENTIFIED BACULOVIRUS HUMAN -- Mutations
P29597 TYK2 UNIDENTIFIED BACULOVIRUS HUMAN -- Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402