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GENERAL
TITLE
NOVEL PYRAZOLE SERIES OF GROUP X SECRETORY PHOSPHOLIPASE A2 (SPLA2-X) INHIBITORS
DATE LAST MODIFIED
4 Apr 2018
RELEASE
15 Oct 2014
OBSOLETE
CLASSIFICATION
HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
66.6
PUBMED ID
DOI
10.1016/J.BMCL.2014.09.058
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O15496 -- ESCHERICHIA COLI HUMAN
GX SPLA2, SPLA2-X, PHOSPHATIDYLCHOLINE 2-ACYLHYDRO ...
Mutations
O15496 -- ESCHERICHIA COLI HUMAN
GX SPLA2, SPLA2-X, PHOSPHATIDYLCHOLINE 2-ACYLHYDRO ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402