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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN MUSCLE L-LACTATE DEHYDROGENASE IN COMPLEX WITH INHIBITOR 1, 3-{[3-CARBAMOYL-7-(2,4-DIMETHOXYPYRIMIDIN-5-YL) QUINOLIN-4-YL]AMINO}BENZOIC ACID
DATE LAST MODIFIED
22 Nov 2017
RELEASE
3 Dec 2014
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 31 2 1
RESOLUTION RANGE HIGH
3.2
RESOLUTION RANGE LOW
34.6
PUBMED ID
DOI
10.1107/S1399004714024791
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
P00338 LDHA, PIG19 ESCHERICHIA COLI HUMAN
LDH-A, CELL PROLIFERATION-INDUCING GENE 19 PROTEIN ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402