4PI3 logo

4PI3

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE ANALYSIS OF CRUZAIN BOUND TO VINYL SULFONE ANALOG OF WRR-483 (WRR-666)
DATE LAST MODIFIED
10 Feb 2016
RELEASE
12 Nov 2014
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
1.27
RESOLUTION RANGE LOW
86.52
PUBMED ID
DOI
10.1021/ACSMEDCHEMLETT.5B00336
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P25779 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CRUZAINE,MAJOR CYSTEINE PROTEINASE
Mutations
P25779 -- ESCHERICHIA COLI TRYPANOSOMA CRUZI
CRUZAINE,MAJOR CYSTEINE PROTEINASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402