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GENERAL
TITLE
STRUCTURE OF AN RBX1-UBC12~NEDD8-CUL1-DCN1 COMPLEX: A RING-E3- E2~UBIQUITIN-LIKE PROTEIN-SUBSTRATE INTERMEDIATE TRAPPED IN ACTION
DATE LAST MODIFIED
29 Jan 2020
RELEASE
2 Jul 2014
OBSOLETE
CLASSIFICATION
LIGASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
3.1
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1016/J.CELL.2014.04.037
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P19054 CUL1 ESCHERICHIA COLI HUMAN
CUL-1
P36924 RBX1, RNF75, ROC1 ESCHERICHIA COLI HUMAN
PROTEIN ZYP,RING FINGER PROTEIN 75,RING-BOX PROTEI ...
D0VWR5 CUL1 ESCHERICHIA COLI HUMAN
CUL-1
P62877 RBX1, RNF75, ROC1 ESCHERICHIA COLI HUMAN
PROTEIN ZYP,RING FINGER PROTEIN 75,RING-BOX PROTEI ...
Mutations
Q13526 DCUN1D1, DCUN1L1, RP42, SCCRO ESCHERICHIA COLI HUMAN
DCUN1 DOMAIN-CONTAINING PROTEIN 1,DEFECTIVE IN CUL ...
P12238 DCUN1D1, DCUN1L1, RP42, SCCRO ESCHERICHIA COLI HUMAN
DCUN1 DOMAIN-CONTAINING PROTEIN 1,DEFECTIVE IN CUL ...
P12238 UBE2M, UBC12 TRICHOPLUSIA NI HUMAN
NEDD8 CARRIER PROTEIN,NEDD8 PROTEIN LIGASE,UBIQUIT ...
P56220 NEDD8 ESCHERICHIA COLI HUMAN
NEDDYLIN,NEURAL PRECURSOR CELL EXPRESSED DEVELOPME ...
D0VWR5 UBE2M, UBC12 TRICHOPLUSIA NI HUMAN
NEDD8 CARRIER PROTEIN,NEDD8 PROTEIN LIGASE,UBIQUIT ...
B9W5G6 NEDD8 ESCHERICHIA COLI HUMAN
NEDDYLIN,NEURAL PRECURSOR CELL EXPRESSED DEVELOPME ...
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402