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3D Structure View

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GENERAL
TITLE
BACK POCKET FLEXIBILITY PROVIDES GROUP-II PAK SELECTIVITY FOR TYPE 1 KINASE INHIBITORS
DATE LAST MODIFIED
26 Feb 2014
RELEASE
12 Feb 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 41 21 2
RESOLUTION RANGE HIGH
2.2
RESOLUTION RANGE LOW
44.62
PUBMED ID
DOI
10.1021/JM401768T

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O96013 PAK4, KIAA1142 ESCHERICHIA COLI HUMAN
P21-ACTIVATED KINASE 4, PAK-4
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402