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GENERAL
TITLE
FRAGMENT-BASED DESIGN OF 3-AMINOPYRIDINE-DERIVED AMIDES AS POTENT INHIBITORS OF HUMAN NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT)
DATE LAST MODIFIED
-
RELEASE
19 Feb 2014
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.72
RESOLUTION RANGE LOW
36.976
PUBMED ID
DOI
10.1016/J.BMCL.2013.12.062

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P43490 NAMPT, PBEF, PBEF1 ESCHERICHIA COLI HUMAN
NAMPRTASE, NAMPT, PRE-B-CELL COLONY-ENHANCING FACT ...
Mutations
P43490 NAMPT, PBEF, PBEF1 ESCHERICHIA COLI HUMAN
NAMPRTASE, NAMPT, PRE-B-CELL COLONY-ENHANCING FACT ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402