4JR5

3D Structure View

CAVITIES

STRUCTURE SETTINGS

LIGANDS

Chain 4JR5_A

Chain 4JR5_B

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GENERAL

TITLE

STRUCTURE-BASED IDENTIFICATION OF UREAS AS NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) INHIBITORS

DATE LAST MODIFIED

10 Jul 2013

RELEASE

8 May 2013

OBSOLETE

CLASSIFICATION

TRANSFERASE/TRANSFERASE INHIBITOR

EXPERIMENT TYPE

X-RAY DIFFRACTION

SPACE GROUP

P 1 21 1

RESOLUTION RANGE HIGH

1.906

RESOLUTION RANGE LOW

106.739

PUBMED ID

DOI

10.1021/JM400186H

PDBe

LIGANDS

Structure Chain	Target Protein	Gene	Expression System	Organism	Synonims	Actions
	P43490	NAMPT, PBEF, PBEF1	ESCHERICHIA COLI	HUMAN	NAMPRTASE, NAMPT, PRE-B-CELL COLONY-ENHANCING FACT ...	Mutations
	P43490	NAMPT, PBEF, PBEF1	ESCHERICHIA COLI	HUMAN	NAMPRTASE, NAMPT, PRE-B-CELL COLONY-ENHANCING FACT ...	Mutations

NGL Viewer is used for the molecular visualization.

AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402