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3D Structure View

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GENERAL
TITLE
CRYSTAL STRUCTURE OF BACE-1 IN COMPLEX WITH 5-CYANO-PYRIDINE-2- CARBOXYLIC ACID [3-((4R,5R,6S)-2-AMINO-5-FLUORO-4-METHYL-6- TRIFLUOROMETHYL-5,6-DIHYDRO-4H-[1,3]OXAZIN-4-YL)-4-FLUORO-PHENYL]- AMIDE
DATE LAST MODIFIED
15 Nov 2017
RELEASE
1 May 2013
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61 2 2
RESOLUTION RANGE HIGH
2.07
RESOLUTION RANGE LOW
49.21
PUBMED ID
DOI
10.1021/JM400225M

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P56817 BACE1, BACE, KIAA1149 ESCHERICHIA COLI HUMAN
ASPARTYL PROTEASE 2, ASP2, ASP 2, BETA-SITE AMYLOI ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402