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GENERAL
TITLE
CRYSTAL STRUCTURE OF INHIBITORY PROTEIN SOCS3 IN COMPLEX WITH JAK2 KINASE DOMAIN AND FRAGMENT OF GP130 INTRACELLULAR DOMAIN
DATE LAST MODIFIED
13 Jun 2018
RELEASE
6 Mar 2013
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
3.9
RESOLUTION RANGE LOW
45.584
PUBMED ID
DOI
10.1038/NSMB.2519
PDBe
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
O60674 JAK2, MCG_9104 SPODOPTERA FRUGIPERDA MOUSE --
O60674 JAK2, MCG_9104 SPODOPTERA FRUGIPERDA MOUSE --
O60674 JAK2, MCG_9104 SPODOPTERA FRUGIPERDA MOUSE --
O60674 JAK2, MCG_9104 SPODOPTERA FRUGIPERDA MOUSE --
O35718 SOCS3, CIS3, CISH3 ESCHERICHIA COLI MOUSE, MOUSE
SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ...
Mutations
O35718 SOCS3, CIS3, CISH3 ESCHERICHIA COLI MOUSE, MOUSE
SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ...
Mutations
O35718 SOCS3, CIS3, CISH3 ESCHERICHIA COLI MOUSE, MOUSE
SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ...
Mutations
O35718 SOCS3, CIS3, CISH3 ESCHERICHIA COLI MOUSE, MOUSE
SOCS-3,CYTOKINE-INDUCIBLE SH2 PROTEIN 3,CIS-3,PROT ...
Mutations
Q00560 -- -- MOUSE
IL-6RB,INTERLEUKIN-6 SIGNAL TRANSDUCER,MEMBRANE GL ...
Mutations
Q00560 -- -- MOUSE
IL-6RB,INTERLEUKIN-6 SIGNAL TRANSDUCER,MEMBRANE GL ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402