4ER6 logo

4ER6

3D Structure View

Loading...

More Info

GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN DOT1L IN COMPLEX WITH INHIBITOR SGC0946
DATE LAST MODIFIED
16 May 2018
RELEASE
16 May 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 65
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
50.148
PUBMED ID
DOI
10.1038/NCOMMS2304

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q8TEK3 DOT1L, KIAA1814, KMT4 ESCHERICHIA COLI HUMAN
DOT1-LIKE PROTEIN, HISTONE H3-K79 METHYLTRANSFERAS ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402