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GENERAL
TITLE
CO-STRUCTURE OF FIBROBLAST GROWTH FACTOR RECEPTOR 1 KINASE DOMAIN WITH 3-(2,6-DICHLORO-3,5-DIMETHOXY-PHENYL)-1-{6-[4-(4-ETHYL-PIPERAZIN-1- YL)-PHENYLAMINO]-PYRIMIDIN-4-YL}-1-METHYL-UREA (BGJ398)
DATE LAST MODIFIED
-
RELEASE
13 Jun 2012
OBSOLETE
CLASSIFICATION
TRANSFERASE/TRANSFERASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
100
PUBMED ID
DOI
10.1021/JM2006222

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P11362 FGFR1, FGFBR, FLG, FLT2 TRICHOPLUSIA NI HUMAN
FGFR-1, BFGF-R-1, FMS-LIKE TYROSINE KINASE 2, FLT- ...
Mutations
P11362 FGFR1, FGFBR, FLG, FLT2 TRICHOPLUSIA NI HUMAN
FGFR-1, BFGF-R-1, FMS-LIKE TYROSINE KINASE 2, FLT- ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402