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GENERAL
TITLE
CRYSTAL STRUCTURE OF HUMAN FXR IN COMPLEX WITH 2-(4-CHLOROPHENYL)-1- [(1S)-1-CYCLOHEXYL-2-(CYCLOHEXYLAMINO)-2-OXOETHYL]-1H-BENZIMIDAZOLE- 6-CARBOXYLIC ACID
DATE LAST MODIFIED
-
RELEASE
29 Dec 2010
OBSOLETE
CLASSIFICATION
HORMONE RECEPTOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 2 2 21
RESOLUTION RANGE HIGH
2.5
RESOLUTION RANGE LOW
46.12
PUBMED ID
DOI
10.1016/J.BMCL.2010.11.039
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q96RI1 NR1H4, HCG_20893 ESCHERICHIA COLI HUMAN
FXR, FARNESOID X-ACTIVATED RECEPTOR, FARNESOL RECE ...
Mutations
Q15788 -- -- --
NCOA-1, CLASS E BASIC HELIX-LOOP-HELIX PROTEIN 74, ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402