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3LG4

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GENERAL
TITLE
STAPHYLOCOCCUS AUREUS V31Y, F92I MUTANT DIHYDROFOLATE REDUCTASE COMPLEXED WITH NADPH AND 5-[(3S)-3-(5-METHOXY-2',6'-DIMETHYLBIPHENYL- 3-YL)BUT-1-YN-1-YL]-6-METHYLPYRIMIDINE-2,4-DIAMINE
DATE LAST MODIFIED
27 Nov 2013
RELEASE
28 Jul 2010
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 61
RESOLUTION RANGE HIGH
3.15
RESOLUTION RANGE LOW
42.84
PUBMED ID
DOI
10.1073/PNAS.1002162107

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P0A017 DFRA, DFRB, FOLA ESCHERICHIA COLI STAPHYLOCOCCUS AUREUS
DHFR
Mutations
P0A017 DFRA, DFRB, FOLA ESCHERICHIA COLI STAPHYLOCOCCUS AUREUS
DHFR
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402