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GENERAL
TITLE
OPTIMIZATION OF ORALLY BIOAVAILABLE ALKYL AMINE RENIN INHIBITORS
DATE LAST MODIFIED
29 Jul 2020
RELEASE
12 Jan 2010
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
1.86
RESOLUTION RANGE LOW
81.11
PUBMED ID
DOI
10.1016/J.BMCL.2009.11.066
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00797 HUMAN_RENIN, REN HOMO SAPIENS HUMAN
ANGIOTENSINOGENASE
Mutations
P00797 HUMAN_RENIN, REN HOMO SAPIENS HUMAN
ANGIOTENSINOGENASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402