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GENERAL
TITLE
CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH THE NON-NUCLEOSIDE RT INHIBITOR (E)-S-METHYL 5-(1-(3,7-DIMETHYL-2- OXO-2,3-DIHYDROBENZO[D]OXAZOL-5-YL)-5-(5-METHYL-1,3,4-OXADIAZOL-2- YL)PENT-1-ENYL)-2-METHOXY-3-METHYLBENZOTHIOATE.
DATE LAST MODIFIED
13 Oct 2021
RELEASE
7 Apr 2010
OBSOLETE
CLASSIFICATION
TRANSFERASE/HYDROLASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
C 1 2 1
RESOLUTION RANGE HIGH
2.8
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1021/JM901167T
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P03366 GAG-POL ESCHERICHIA COLI BL21(DE3) HIV-1
P66 RT
Mutations
P03366 GAG-POL ESCHERICHIA COLI BL21(DE3) HIV-1
P51 RT
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402