3EY4 logo

3EY4

3D Structure View

Loading...

More Info

GENERAL
TITLE
FURTHER STUDIES WITH THE 2-AMINO-1,3-THIAZOL-4(5H)-ONE CLASS OF 11- HYDROXYSTEROID DEHYDROGENASE TYPE 1 (11-HSD1) INHIBITORS: REDUCING PREGNANE X RECEPTOR (PXR) ACTIVITY AND EXPLORING ACTIVITY IN A MONKEY PHARMACODYNAMIC MODEL
DATE LAST MODIFIED
20 Oct 2021
RELEASE
11 Nov 2008
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
50
PUBMED ID
-
DOI
--

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P28845 HSD11B1, HSD11, HSD11L ESCHERICHIA COLI HUMAN
CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, 11 ...
Mutations
P28845 HSD11B1, HSD11, HSD11L ESCHERICHIA COLI HUMAN
CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, 11 ...
Mutations
P28845 HSD11B1, HSD11, HSD11L ESCHERICHIA COLI HUMAN
CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, 11 ...
Mutations
P28845 HSD11B1, HSD11, HSD11L ESCHERICHIA COLI HUMAN
CORTICOSTEROID 11-BETA-DEHYDROGENASE ISOZYME 1, 11 ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402