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GENERAL
TITLE
INHIBITION OF THE HSP90 MOLECULAR CHAPERONE IN VITRO AND IN VIVO BY NOVEL, SYNTHETIC, POTENT RESORCINYLIC PYRAZOLE, ISOXAZOLE AMIDE ANALOGS
DATE LAST MODIFIED
28 Feb 2018
RELEASE
24 Apr 2007
OBSOLETE
CLASSIFICATION
CHAPERONE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
I 2 2 2
RESOLUTION RANGE HIGH
1.9
RESOLUTION RANGE LOW
65.94
PUBMED ID
DOI
10.1158/1535-7163.MCT-07-0149
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P07900 -- ESCHERICHIA COLI HUMAN
HEAT SHOCK PROTEIN HSP90-ALPHA, HSP 86, RENAL CARC ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402