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3D Structure View

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GENERAL
TITLE
COMPLEX OF ALDOSE REDUCTASE WITH NADP+ AND SIMALTANEOUSLY BOUND COMPETETIVE INHIBITORS FIDARESTAT AND IDD594. CONCENTRATION OF FIDARESTAT IN SOAKING SOLUTION IS LESS THAN CONCENTRATION OF IDD594.
DATE LAST MODIFIED
17 Oct 2012
RELEASE
17 Apr 2007
OBSOLETE
CLASSIFICATION
OXIDOREDUCTASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
0.85
RESOLUTION RANGE LOW
50
PUBMED ID
DOI
10.1002/PROT.24136

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P15121 AKR1B1, ALDR1 ESCHERICHIA COLI HUMAN
AR, ALDEHYDE REDUCTASE
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402