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GENERAL
TITLE
CARBONIC ANHYDRASE ACTIVATORS. ACTIVATION OF ISOFORMS I, II, IV, VA, VII AND XIV WITH L- AND D- PHENYLALANINE AND CRYSTALLOGRAPHIC ANALYSIS OF THEIR ADDUCTS WITH ISOZYME II: STEROSPECIFIC RECOGNITION WITHIN THE ACTIVE SITE OF AN ENZYME AND ITS CONSEQUENCES FOR THE DRUG DESIGN, STRUCTURE WITH L-PHENYLALANINE
DATE LAST MODIFIED
4 Apr 2018
RELEASE
23 May 2006
OBSOLETE
CLASSIFICATION
LYASE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
1.6
RESOLUTION RANGE LOW
15
PUBMED ID
DOI
10.1021/JM0603320
PDBe
--
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P00918 -- -- HUMAN
CARBONIC ANHYDRASE II, CARBONATE DEHYDRATASE II, C ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402