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GENERAL
TITLE
DIFFERENTIAL BINDING OF INHIBITORS TO ACTIVE AND INACTIVE CDK2 PROVIDES INSIGHTS FOR DRUG DESIGN
DATE LAST MODIFIED
3 Apr 2019
RELEASE
1 Mar 2006
OBSOLETE
CLASSIFICATION
TRANSFERASE/INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 21 21 21
RESOLUTION RANGE HIGH
2.9
RESOLUTION RANGE LOW
20
PUBMED ID
DOI
10.1016/J.CHEMBIOL.2005.11.011
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P24941 -- SPODOPTERA FRUGIPERDA HUMAN
CYCLIN DEPENDENT KINASE 2, P33 PROTEIN KINASE
Mutations
P20248 -- ESCHERICHIA COLI HUMAN
CYCLIN A
Mutations
P24941 -- SPODOPTERA FRUGIPERDA HUMAN
CYCLIN DEPENDENT KINASE 2, P33 PROTEIN KINASE
Mutations
P20248 -- ESCHERICHIA COLI HUMAN
CYCLIN A
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402