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GENERAL
TITLE
STRUCTURAL MECHANISM FOR THE INHIBITION OF CDK5-P25 BY ROSCOVITINE, ALOISINE AND INDIRUBIN.
DATE LAST MODIFIED
13 Jul 2011
RELEASE
10 Nov 2004
OBSOLETE
CLASSIFICATION
CELL CYCLE
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 32 2 1
RESOLUTION RANGE HIGH
2.3
RESOLUTION RANGE LOW
25
PUBMED ID
DOI
10.1021/JM049323M
LIGANDS

Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
Q00535 -- SPODOPTERA FRUGIPERDA HUMAN
TAU PROTEIN KINASE II, TPKII CATALYTIC, SERINE/THR ...
Mutations
Q00535 -- SPODOPTERA FRUGIPERDA HUMAN
TAU PROTEIN KINASE II, TPKII CATALYTIC, SERINE/THR ...
Mutations
Q15078 -- SPODOPTERA FRUGIPERDA HUMAN
CDK5 ACTIVATOR 1, CYCLIN-DEPENDENT KINASE 5 REGULA ...
Mutations
Q15078 -- SPODOPTERA FRUGIPERDA HUMAN
CDK5 ACTIVATOR 1, CYCLIN-DEPENDENT KINASE 5 REGULA ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402