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3D Structure View

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GENERAL
TITLE
CRYSTAL STRUCTURE OF EPOXOMICIN:20S PROTEASOME REVEALS A MOLECULAR BASIS FOR SELECTIVITY OF ALPHA,BETA-EPOXYKETONE PROTEASOME INHIBITORS
DATE LAST MODIFIED
8 Feb 2012
RELEASE
27 Nov 2000
OBSOLETE
CLASSIFICATION
HYDROLASE/HYDROLASE INHIBITOR
EXPERIMENT TYPE
X-RAY DIFFRACTION
SPACE GROUP
P 1 21 1
RESOLUTION RANGE HIGH
2.25
RESOLUTION RANGE LOW
20
PUBMED ID
-
DOI
10.1021/JA993588M
PDBe
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Chains

Structure ChainTarget ProteinGeneExpression SystemOrganismSynonimsActions
P30657 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT PRE4, MULTICATALYTIC ENDOPEPTIDA ...
Mutations
P38624 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT PRE3, MULTICATALYTIC ENDOPEPTIDA ...
Mutations
-- -- -- --
-- -- -- --
P23639 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT Y7, MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
P23638 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT Y13, MULTICATALYTIC ENDOPEPTIDAS ...
Mutations
P40303 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT PRE6, MULTICATALYTIC ENDOPEPTIDA ...
Mutations
P32379 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT PUP2, MULTICATALYTIC ENDOPEPTIDA ...
Mutations
P40302 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT PRE5, MULTICATALYTIC ENDOPEPTIDA ...
Mutations
P21242 -- -- BAKER'S YEAST
MACROPAIN SUBUNIT C1, MULTICATALYTIC ENDOPEPTIDASE ...
Mutations
NGL Viewer is used for the molecular visualization.
  • AS Rose, AR Bradley, Y Valasatava, JM Duarte, A Prlić and PW Rose. NGL viewer: web-based molecular graphics for large complexes. Bioinformatics: bty419, 2018. doi:10.1093/bioinformatics/bty419
  • AS Rose and PW Hildebrand. NGL Viewer: a web application for molecular visualization. Nucl Acids Res (1 July 2015) 43 (W1): W576-W579 first published online April 29, 2015. doi:10.1093/nar/gkv402