Navitoclax
FEATURES
Loading...
NAMES
  • ABT-263
  • NAVITOCLAX
SMILES
CN(C)CC[C@H](CSc1ccccc1)Nc1ccc(S(=O)(=O)NC(=O)c2ccc(N3CCN(CC4=C(c5ccc(Cl)cc5)CCCC4(C)C)CC3)cc2)cc1S(=O)(=O)C(F)(F)F
InChI
InChI=1S/C45H53ClF3N5O5S3/c1-44(2)23-8-11-39(32-12-16-34(46)17-13-32)40(44)30-53-25-27-54(28-26-53)36-18-14-33(15-19-36)43(55)51-62(58,59)38-20-21-41(42(29-38)61(56,57)45(47,48)49)50-35(22-24-52(3)4)31-60-37-9-6-5-7-10-37/h5-7,9-10,12-21,29,35,50H,8,11,22-28,30-31H2,1-4H3,(H,51,55)/t35-/m1/s1
MOLECULAR FORMULA
C45H53ClF3N5O5S3
CROSS REFERENCES
Loading...
Navitoclax
Compound Synopsis
OVERVIEW
PROPERTIES
Molecular weight931.28
AlogP9.06
HBond donors2
HBond acceptors10
Atoms115
Contains toxicophoreYes
Contains PAINSNo
Commercially availableUnknown
Property color indications are based on Lipinski's Ro5.
PROTEIN TARGETS
No information about proteins targeted by Navitoclax.