2032987 logo
8LN
FEATURES
Loading...
avatar
avatar
avatar
avatar
avatar
avatar
avatar
avatar
avatar
avatar
avatar
NAMES
  • 8LN
SMILES
Cc1nn(C2CCNCC2)cc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1
InChI
InChI=1S/C20H21ClN8/c1-13-16(12-29(27-13)14-5-7-22-8-6-14)25-20-24-10-15(21)19(26-20)17-11-23-18-4-2-3-9-28(17)18/h2-4,9-12,14,22H,5-8H2,1H3,(H,24,25,26)
MOLECULAR FORMULA
C20H21ClN8
CROSS REFERENCES

8LN - target affinity plot

*Select a region to zoom

8LN - target affinity table

ProteinProtein familyMean PotencyMost Potent ValueLeast Potent ValueSample count
IGF1R IGF1Rprotein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. 46 nM 38 nM 54 nM 2
CDK2 CDK2protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. 392 nM 392 nM 392 nM 1
KCNH2 KCNH2potassium channel family. H (Eag) (TC 1.A.1.20) subfamily. Kv11.1/KCNH2 sub-subfamily. 29,000 nM 29,000 nM 29,000 nM 1